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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP9A
All Species:
19.09
Human Site:
S249
Identified Species:
35
UniProt:
O75110
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75110
NP_006036.1
1047
118583
S249
E
D
S
D
P
P
I
S
E
S
L
S
I
E
N
Chimpanzee
Pan troglodytes
XP_514727
875
98509
Y103
T
V
V
G
V
V
L
Y
T
G
R
E
L
R
S
Rhesus Macaque
Macaca mulatta
XP_001098852
1044
118009
S246
E
D
S
D
P
P
I
S
E
S
L
S
I
E
N
Dog
Lupus familis
XP_534457
1043
118292
S245
E
D
S
D
P
P
I
S
E
S
L
S
I
E
N
Cat
Felis silvestris
Mouse
Mus musculus
O70228
1047
118590
S249
E
D
S
D
P
P
I
S
E
S
L
S
I
E
N
Rat
Rattus norvegicus
XP_002726328
995
111897
G223
I
D
I
H
N
F
L
G
T
F
T
R
V
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509092
1116
127035
S318
E
D
S
D
P
P
V
S
E
S
L
S
I
E
N
Chicken
Gallus gallus
XP_417508
1115
125396
N317
E
D
S
D
P
S
V
N
E
S
L
S
I
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038619
1108
125101
H296
E
D
C
D
P
P
I
H
E
S
L
S
I
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396589
1276
146194
E457
R
Y
D
G
Y
S
S
E
E
S
L
G
V
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799223
1105
125600
Q307
L
E
E
G
V
S
T
Q
D
A
L
G
I
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P98205
1107
124818
W233
C
Y
L
R
N
T
E
W
A
C
G
V
S
V
Y
Baker's Yeast
Sacchar. cerevisiae
P40527
1151
130199
P361
Y
K
D
S
T
S
N
P
L
S
V
D
N
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
97.8
97.4
N.A.
97.9
89.7
N.A.
90.2
89.5
N.A.
71.3
N.A.
N.A.
54.3
N.A.
60.4
Protein Similarity:
100
83.5
98.2
98.2
N.A.
99.5
91.8
N.A.
92.2
91.5
N.A.
82.4
N.A.
N.A.
66.8
N.A.
74.4
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
93.3
80
N.A.
86.6
N.A.
N.A.
26.6
N.A.
26.6
P-Site Similarity:
100
20
100
100
N.A.
100
26.6
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
44.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
62.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
62
16
54
0
0
0
0
8
0
0
8
0
8
0
% D
% Glu:
54
8
8
0
0
0
8
8
62
0
0
8
0
62
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
24
0
0
0
8
0
8
8
16
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
39
0
0
0
0
0
62
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
16
0
8
0
70
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
8
8
0
0
0
0
8
8
70
% N
% Pro:
0
0
0
0
54
47
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
8
8
0
8
0
% R
% Ser:
0
0
47
8
0
31
8
39
0
70
0
54
8
0
16
% S
% Thr:
8
0
0
0
8
8
8
0
16
0
8
0
0
8
0
% T
% Val:
0
8
8
0
16
8
16
0
0
0
8
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
16
0
0
8
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _